首页 > 试剂耗材 > Gadospin F MRI动脉粥样硬化成像造影剂

GadoSpin F是针对动脉粥样硬化开发的独一无二的MRI造影剂。它包含了疏水部分用于蛋白结合。该造影剂有效的累积在动脉硬化斑块处,能够直接用于T1加权成像。

Gadospin F.jpg 

(右图)MRI(TFL IR ,1.5T)T1加权成像,在6小时和24小时注射GadoSpin F后,兔子动脉粥样硬化斑块检测。

(左图):T1 加权MRI成像, GadoSin F高分辨率小鼠血管成像。


参考文献

1. Zheng, J.et al.(2008) Targeted contrast agent helps to monitor advanced plague during progressiona magnetic resonance imaging study in rabbits. Invest. Radiol. 43:49-55.

2. Raatschen, H.J.et al (2006) MR1 tumor characterization using Gd-GlyMe-DOTA-perfluofooctyl-mannose conjugate (Gadofluorine M), a protein-avid contrast agent. Contrast Media Mol. Imaging 1:113-120.

3. Barkhausen, J.et al (2003) Deteaion of atherosclerotic plaque with Gadofluorine-enhanced magnetic resonance imaging. Circulation 108:605-609.



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